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The Putative HORMA Domain Protein Atg101 Dimerizes and Is Required for Starvation-Induced and Selective Autophagy in Drosophila

The large-scale turnover of intracellular material including organelles is achieved by autophagy-mediated degradation in lysosomes. Initiation of autophagy is controlled by a protein kinase complex consisting of an Atg1-family kinase, Atg13, FIP200/Atg17, and the metazoan-specific subunit Atg101. He...

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Detalles Bibliográficos
Autores principales: Hegedűs, Krisztina, Nagy, Péter, Gáspári, Zoltán, Juhász, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034400/
https://www.ncbi.nlm.nih.gov/pubmed/24895579
http://dx.doi.org/10.1155/2014/470482