PIP(2) regulation of KCNQ channels: biophysical and molecular mechanisms for lipid modulation of voltage-dependent gating

Voltage-gated potassium (Kv) channels contain voltage-sensing (VSD) and pore-gate (PGD) structural domains. During voltage-dependent gating, conformational changes in the two domains are coupled giving rise to voltage-dependent opening of the channel. In addition to membrane voltage, KCNQ (Kv7) chan...

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Detalles Bibliográficos
Autores principales: Zaydman, Mark A., Cui, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034418/
https://www.ncbi.nlm.nih.gov/pubmed/24904429
http://dx.doi.org/10.3389/fphys.2014.00195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034418/
https://www.ncbi.nlm.nih.gov/pubmed/24904429
http://dx.doi.org/10.3389/fphys.2014.00195

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