Overcoming co-product inhibition in the nicotinamide independent asymmetric bioreduction of activated C=C-bonds using flavin-dependent ene-reductases

Eleven flavoproteins from the old yellow enzyme family were found to catalyze the disproportionation (“dismutation”) of conjugated enones. Incomplete conversions, which were attributed to enzyme inhibition by the co-product phenol could be circumvented via in situ co-product removal by scavenging th...

Descripción completa

Detalles Bibliográficos
Autores principales: Winkler, Christoph K, Clay, Dorina, van Heerden, Esta, Faber, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034509/
https://www.ncbi.nlm.nih.gov/pubmed/23794404
http://dx.doi.org/10.1002/bit.24981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034509/
https://www.ncbi.nlm.nih.gov/pubmed/23794404
http://dx.doi.org/10.1002/bit.24981

Ejemplares similares