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Ancestry runs deeper than blood: The evolutionary history of ABO points to cryptic variation of functional importance

The ABO histo-blood group, first discovered over a century ago, is found not only in humans but also in many other primate species, with the same genetic variants maintained for at least 20 million years. Polymorphisms in ABO have been associated with susceptibility to a large number of human diseas...

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Detalles Bibliográficos
Autores principales: Ségurel, Laure, Gao, Ziyue, Przeworski, Molly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034584/
https://www.ncbi.nlm.nih.gov/pubmed/23836453
http://dx.doi.org/10.1002/bies.201300030