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Conditionally unbiased and near unbiased estimation of the selected treatment mean for multistage drop-the-losers trials
The two-stage drop-the-loser design provides a framework for selecting the most promising of K experimental treatments in stage one, in order to test it against a control in a confirmatory analysis at stage two. The multistage drop-the-losers design is both a natural extension of the original two-st...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BlackWell Publishing Ltd
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034592/ https://www.ncbi.nlm.nih.gov/pubmed/24353149 http://dx.doi.org/10.1002/bimj.201200245 |