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In Silico Investigation of Cytochrome P450 2C9 in relation to Aging Using Traditional Chinese Medicine

Cytochrome P450 2C9 (CYP2C9) metabolizes dehydroepiandrosterone-sulfate (DHEA-S), but in elderly people the amount of DHEA-S remaining after CYP2C9 metabolization may be insufficient for optimal health. A prediction model, molecular docking, and molecular dynamics were used to screen the Traditional...

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Detalles Bibliográficos
Autores principales: Hung, Tzu-Chieh, Kuo, Chia-Chen, Chen, Calvin Yu-Chian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034651/
https://www.ncbi.nlm.nih.gov/pubmed/24899908
http://dx.doi.org/10.1155/2014/404505