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In Silico Investigation of Cytochrome P450 2C9 in relation to Aging Using Traditional Chinese Medicine
Cytochrome P450 2C9 (CYP2C9) metabolizes dehydroepiandrosterone-sulfate (DHEA-S), but in elderly people the amount of DHEA-S remaining after CYP2C9 metabolization may be insufficient for optimal health. A prediction model, molecular docking, and molecular dynamics were used to screen the Traditional...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034651/ https://www.ncbi.nlm.nih.gov/pubmed/24899908 http://dx.doi.org/10.1155/2014/404505 |