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Inference of high resolution HLA types using genome-wide RNA or DNA sequencing reads

BACKGROUND: Accurate HLA typing at amino acid level (four-digit resolution) is critical in hematopoietic and organ transplantations, pathogenesis studies of autoimmune and infectious diseases, as well as the development of immunoncology therapies. With the rapid adoption of genome-wide sequencing in...

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Detalles Bibliográficos
Autores principales: Bai, Yu, Ni, Min, Cooper, Blerta, Wei, Yi, Fury, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035057/
https://www.ncbi.nlm.nih.gov/pubmed/24884790
http://dx.doi.org/10.1186/1471-2164-15-325