Nucleosome positioning and histone modifications define relationships between regulatory elements and nearby gene expression in breast epithelial cells

BACKGROUND: The precise nature of how cell type specific chromatin structures at enhancer sites affect gene expression is largely unknown. Here we identified cell type specific enhancers coupled with gene expression in two different types of breast epithelial cells, HMEC (normal breast epithelial ce...

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Detalles Bibliográficos
Autores principales: Rhie, Suhn Kyong, Hazelett, Dennis J, Coetzee, Simon G, Yan, Chunli, Noushmehr, Houtan, Coetzee, Gerhard A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035062/
https://www.ncbi.nlm.nih.gov/pubmed/24885402
http://dx.doi.org/10.1186/1471-2164-15-331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035062/
https://www.ncbi.nlm.nih.gov/pubmed/24885402
http://dx.doi.org/10.1186/1471-2164-15-331

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