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Discovery of transgene insertion sites by high throughput sequencing of mate pair libraries
BACKGROUND: Transgenesis by random integration of a transgene into the genome of a zygote has become a reliable and powerful method for the creation of new mouse strains that express exogenous genes, including human disease genes, tissue specific reporter genes or genes that allow for tissue specifi...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035081/ https://www.ncbi.nlm.nih.gov/pubmed/24884803 http://dx.doi.org/10.1186/1471-2164-15-367 |