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Discovery of transgene insertion sites by high throughput sequencing of mate pair libraries

BACKGROUND: Transgenesis by random integration of a transgene into the genome of a zygote has become a reliable and powerful method for the creation of new mouse strains that express exogenous genes, including human disease genes, tissue specific reporter genes or genes that allow for tissue specifi...

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Detalles Bibliográficos
Autores principales:	Srivastava, Anuj, Philip, Vivek M, Greenstein, Ian, Rowe, Lucy B, Barter, Mary, Lutz, Cathleen, Reinholdt, Laura G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035081/ https://www.ncbi.nlm.nih.gov/pubmed/24884803 http://dx.doi.org/10.1186/1471-2164-15-367

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