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Early white matter changes in CADASIL: evidence of segmental intramyelinic oedema in a pre-clinical mouse model

INTRODUCTION: Small vessel disease (SVD) of the brain is a leading cause of age- and hypertension-related cognitive decline and disability. Cerebral white matter changes are a consistent manifestation of SVD on neuroimaging, progressing silently for many years before becoming clinically evident. The...

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Detalles Bibliográficos
Autores principales: Cognat, Emmanuel, Cleophax, Sabine, Domenga-Denier, Valérie, Joutel, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035092/
https://www.ncbi.nlm.nih.gov/pubmed/24886907
http://dx.doi.org/10.1186/2051-5960-2-49