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Network Analyses Reveal Pervasive Functional Regulation Between Proteases in the Human Protease Web

Proteolytic processing is an irreversible posttranslational modification affecting a large portion of the proteome. Protease-cleaved mediators frequently exhibit altered activity, and biological pathways are often regulated by proteolytic processing. Many of these mechanisms have not been appreciate...

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Detalles Bibliográficos
Autores principales: Fortelny, Nikolaus, Cox, Jennifer H., Kappelhoff, Reinhild, Starr, Amanda E., Lange, Philipp F., Pavlidis, Paul, Overall, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035269/
https://www.ncbi.nlm.nih.gov/pubmed/24865846
http://dx.doi.org/10.1371/journal.pbio.1001869