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Protein Flexibility Facilitates Quaternary Structure Assembly and Evolution

The intrinsic flexibility of proteins allows them to undergo large conformational fluctuations in solution or upon interaction with other molecules. Proteins also commonly assemble into complexes with diverse quaternary structure arrangements. Here we investigate how the flexibility of individual pr...

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Detalles Bibliográficos
Autores principales: Marsh, Joseph A., Teichmann, Sarah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035275/
https://www.ncbi.nlm.nih.gov/pubmed/24866000
http://dx.doi.org/10.1371/journal.pbio.1001870