A time- and matrix-dependent TGFBR3–JUND–KRT5 regulatory circuit in single breast epithelial cells and basal-like premalignancies

Basal-like breast carcinoma is characterized by poor prognosis and high intratumor heterogeneity. In an immortalized basal-like breast epithelial cell line, we identified two anti-correlated gene-expression programs that arise among single extracellular matrix (ECM)-attached cells during organotypic...

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Detalles Bibliográficos
Autores principales: Wang, Chun-Chao, Bajikar, Sameer S., Jamal, Leen, Atkins, Kristen A., Janes, Kevin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035356/
https://www.ncbi.nlm.nih.gov/pubmed/24658685
http://dx.doi.org/10.1038/ncb2930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035356/
https://www.ncbi.nlm.nih.gov/pubmed/24658685
http://dx.doi.org/10.1038/ncb2930

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