Roles of SLX1–SLX4, MUS81–EME1, and GEN1 in avoiding genome instability and mitotic catastrophe

The resolution of recombination intermediates containing Holliday junctions (HJs) is critical for genome maintenance and proper chromosome segregation. Three pathways for HJ processing exist in human cells and involve the following enzymes/complexes: BLM–TopoIIIα–RMI1–RMI2 (BTR complex), SLX1–SLX4–M...

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Detalles Bibliográficos
Autores principales: Sarbajna, Shriparna, Davies, Derek, West, Stephen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035540/
https://www.ncbi.nlm.nih.gov/pubmed/24831703
http://dx.doi.org/10.1101/gad.238303.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035540/
https://www.ncbi.nlm.nih.gov/pubmed/24831703
http://dx.doi.org/10.1101/gad.238303.114

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