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Quercetin and Sorafenib as a Novel and Effective Couple in Programmed Cell Death Induction in Human Gliomas

The aim of the present study was to investigate the effect of sorafenib and quercetin on the induction of apoptosis and autophagy in human anaplastic astrocytoma (MOGGCCM) and glioblastoma multiforme (T98G) cell lines. In MOGGCCM cells, sorafenib initiated mainly apoptosis, mediated by the mitochond...

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Detalles Bibliográficos
Autores principales: Jakubowicz-Gil, Joanna, Langner, Ewa, Bądziul, Dorota, Wertel, Iwona, Rzeski, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035551/
https://www.ncbi.nlm.nih.gov/pubmed/24366851
http://dx.doi.org/10.1007/s12640-013-9452-x