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Quantitative phenotypic and pathway profiling guides rational drug combination strategies
Advances in target-based drug discovery strategies have enabled drug discovery groups in academia and industry to become very effective at generating molecules that are potent and selective against single targets. However, it has become apparent from disappointing results in recent clinical trials t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035564/ https://www.ncbi.nlm.nih.gov/pubmed/24904421 http://dx.doi.org/10.3389/fphar.2014.00118 |