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Inhibitors of enhancer of zeste homolog 2 (EZH2) activate tumor-suppressor microRNAs in human cancer cells

Enhancer of zeste homolog 2 (EZH2) enhances tumorigenesis and is commonly overexpressed in several types of cancer. To investigate the anticancer effects of EZH2 inhibitors, microRNA (miRNA) expression profiles were examined in gastric and liver cancer cells treated with suberoylanilide hydroxamic a...

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Detalles Bibliográficos
Autores principales: Hibino, S, Saito, Y, Muramatsu, T, Otani, A, Kasai, Y, Kimura, M, Saito, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035694/
https://www.ncbi.nlm.nih.gov/pubmed/24861464
http://dx.doi.org/10.1038/oncsis.2014.17