Cargando…

Inhibitors of enhancer of zeste homolog 2 (EZH2) activate tumor-suppressor microRNAs in human cancer cells

Enhancer of zeste homolog 2 (EZH2) enhances tumorigenesis and is commonly overexpressed in several types of cancer. To investigate the anticancer effects of EZH2 inhibitors, microRNA (miRNA) expression profiles were examined in gastric and liver cancer cells treated with suberoylanilide hydroxamic a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hibino, S, Saito, Y, Muramatsu, T, Otani, A, Kasai, Y, Kimura, M, Saito, H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035694/ https://www.ncbi.nlm.nih.gov/pubmed/24861464 http://dx.doi.org/10.1038/oncsis.2014.17

Ejemplares similares

MicroRNA-137 acts as a tumor suppressor in osteosarcoma by targeting enhancer of zeste homolog 2
por: Feng, Qiong, et al.
Publicado: (2017)

MicroRNA-137 acts as a tumor suppressor in osteosarcoma by targeting enhancer of zeste homolog 2
por: Feng, Qiong, et al.
Publicado: (2021)

Enhancer of Zeste homolog 2 (EZH2) induces epithelial-mesenchymal transition in endometriosis
por: Zhang, Qi, et al.
Publicado: (2017)

Expression of Enhancer of Zeste Homolog 2 (EZH2) Gene in Acute Myeloid Leukemia
por: Hamed, Nahla A. M., et al.
Publicado: (2023)

Enhancer of zeste homolog 2 (EZH2) in pediatric soft tissue sarcomas: first implications
por: Ciarapica, Roberta, et al.
Publicado: (2011)

Enhancer of Zeste Homolog 2 (EZH2) Mediates Glucolipotoxicity-Induced Apoptosis in β-Cells
por: Dahlby, Tina, et al.
Publicado: (2020)

Enhancer of zeste homolog 2 (EZH2) expression is an independent prognostic factor in renal cell carcinoma
por: Wagener, Nina, et al.
Publicado: (2010)

Effects of Enhancer of Zeste Homolog 2 (EZH2) Expression on Brain Glioma Cell Proliferation and Tumorigenesis
por: Cheng, Tianci, et al.
Publicado: (2018)

Promotion of Glioblastoma Cell Motility by Enhancer of Zeste Homolog 2 (EZH2) Is Mediated by AXL Receptor Kinase
por: Ott, Martina, et al.
Publicado: (2012)

Downregulation of Enhancer of Zeste Homolog 2 (EZH2) is essential for the Induction of Autophagy and Apoptosis in Colorectal Cancer Cells
por: Yao, Yizhou, et al.
Publicado: (2016)

A systems approach identifies Enhancer of Zeste Homolog 2 (EZH2) as a protective factor in epilepsy
por: Khan, Nadia, et al.
Publicado: (2019)

Differential expression of microRNA, miR-150 and enhancer of zeste homolog 2 (EZH2) in peripheral blood cells as early prognostic markers of severe forms of dengue
por: Hapugaswatta, Harsha, et al.
Publicado: (2020)

Evaluation of Immunohistochemical Expression of Enhancer of Zeste Homolog 2 (EZH2) and Its Association With Clinicopathological Variables in Carcinoma Cervix
por: Priya, Aditi, et al.
Publicado: (2023)

Suppressor of Zeste 12 homolog RNA interference inhibits retinoblastoma cell invasion
por: ZHOU, MIN, et al.
Publicado: (2014)

Analysis of the correlation between Zeste enhancer homolog 2 (EZH2) mRNA expression and the prognosis of mesothelioma patients and immune infiltration
por: Fan, Kui, et al.
Publicado: (2022)

Enhancer of Zeste Homolog 2 (EZH2) Is a Marker of High-Grade Neuroendocrine Neoplasia in Gastroenteropancreatic and Pulmonary Tract and Predicts Poor Prognosis
por: Bremer, Sebastian C. B., et al.
Publicado: (2022)

Targeting enhancer of zeste homolog 2 protects against acute kidney injury
por: Zhou, X., et al.
Publicado: (2018)

Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98
por: Alajez, N M, et al.
Publicado: (2010)

MicroRNA-26a suppresses epithelial-mesenchymal transition in human hepatocellular carcinoma by repressing enhancer of zeste homolog 2
por: Ma, De-Ning, et al.
Publicado: (2016)

Enhancer of zeste homolog 2 is involved in the proliferation of endometrial carcinoma
por: JIA, NAN, et al.
Publicado: (2014)

MicroRNA-98 and microRNA-214 post-transcriptionally regulate enhancer of zeste homolog 2 and inhibit migration and invasion in human esophageal squamous cell carcinoma
por: Huang, Sheng-Dong, et al.
Publicado: (2012)

Poorly differentiated synovial sarcoma is associated with high expression of enhancer of zeste homologue 2 (EZH2)
por: Changchien, Yi-Che, et al.
Publicado: (2012)

EZH2 inhibition in multiple myeloma downregulates myeloma associated oncogenes and upregulates microRNAs with potential tumor suppressor functions
por: Alzrigat, Mohammad, et al.
Publicado: (2016)

MicroRNAs in Hepatobiliary and Pancreatic Cancers
por: Saito, Yoshimasa, et al.
Publicado: (2011)

Oncogenic roles of enhancer of zeste homolog 1/2 in hematological malignancies
por: Nakagawa, Makoto, et al.
Publicado: (2018)

Novel Natural Inhibitors Targeting Enhancer of Zeste Homolog 2: A Comprehensive Structural Biology Research
por: Li, Weihang, et al.
Publicado: (2021)

Uropathogenic E.coli (UPEC) Infection Induces Proliferation through Enhancer of Zeste Homologue 2 (EZH2)
por: Ting, Kenneth, et al.
Publicado: (2016)

Silencing the enhancer of zeste homologue 2, Ezh2, represses axon regeneration of dorsal root ganglion neurons
por: Guo, Ting-Ting, et al.
Publicado: (2021)

MicroRNA-362-5p enhances the cisplatin sensitivity of gastric cancer cells by targeting suppressor of zeste 12 protein
por: Wei, Xiaoli, et al.
Publicado: (2019)

Impact of Enhancer of Zeste Homolog 2 on T Helper Cell-Mediated Allergic Rhinitis
por: Hou, Tsung-Yun, et al.
Publicado: (2017)

Cluster microRNAs miR‐194 and miR‐215 suppress the tumorigenicity of intestinal tumor organoids
por: Nakaoka, Toshiaki, et al.
Publicado: (2017)

Six-transmembrane epithelial antigen of the prostate and enhancer of zeste homolog 2 as immunotherapeutic targets for lung cancer
por: Hayashi, Satoshi, et al.
Publicado: (2011)

Enhancer of Zeste Homologue 2 (EZH2) Down-regulates RUNX3 by Increasing Histone H3 Methylation
por: Fujii, Satoshi, et al.
Publicado: (2008)

Enhancer of zeste homologue 2 (EZH2) is a reliable immunohistochemical marker to differentiate malignant and benign hepatic tumors
por: Hajósi-Kalcakosz, Szofia, et al.
Publicado: (2012)

The Effect of Overexpression of the Enhancer of Zeste Homolog 1 (EZH1) Gene on Aristolochic Acid-Induced Injury in HK-2 Human Kidney Proximal Tubule Cells In Vitro
por: Wang, Liping, et al.
Publicado: (2019)

Enhancer of zeste homolog 2 activates wnt signaling through downregulating CXXC finger protein 4
por: Lu, H, et al.
Publicado: (2013)

Enhancer of Zeste Homolog 2 (EZH2) Contributes to Rod Photoreceptor Death Process in Several Forms of Retinal Degeneration and Its Activity Can Serve as a Biomarker for Therapy Efficacy
por: Mbefo, Martial, et al.
Publicado: (2021)

Enhancer of Zeste Homolog 2 Induces Pulmonary Artery Smooth Muscle Cell Proliferation
por: Aljubran, Salman A., et al.
Publicado: (2012)

Enhancer of Zeste Homolog 2 as an Independent Prognostic Marker for Cancer: A Meta-Analysis
por: Chen, Shuling, et al.
Publicado: (2015)

Enhancer of zeste homolog 2 silencing inhibits tumor growth and lung metastasis in osteosarcoma
por: Lv, Yang-Fan, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_6369uqla1esdvsp8dkhe7pbfk5