CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells

BACKGROUND: Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene lead to the disease cystic fibrosis (CF). Although patients with CF often have disturbances in glucose metabolism including impaired insulin release, no previous studies have tested the hypothesis that CFTR...

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Detalles Bibliográficos
Autores principales: Edlund, Anna, Esguerra, Jonathan LS, Wendt, Anna, Flodström-Tullberg, Malin, Eliasson, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035698/
https://www.ncbi.nlm.nih.gov/pubmed/24885604
http://dx.doi.org/10.1186/1741-7015-12-87

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035698/
https://www.ncbi.nlm.nih.gov/pubmed/24885604
http://dx.doi.org/10.1186/1741-7015-12-87

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