Cargando…

Ciprofloxacin has antifibrotic effects in scleroderma fibroblasts via downregulation of Dnmt1 and upregulation of Fli1

Systemic sclerosis (SSc) is characterized by fibrosis of the skin and internal organs. The present study was undertaken to examine the effects of ciprofloxacin, a fluoroquinolone antibiotic implicated in matrix remodeling, on dermal and lung fibroblasts obtained from SSc patients. Dermal and lung fi...

Descripción completa

Detalles Bibliográficos
Autores principales: BUJOR, ANDREEA M., HAINES, PAUL, PADILLA, CRISTINA, CHRISTMANN, ROMY B., JUNIE, MONICA, SAMPAIO-BARROS, PERCIVAL D., LAFYATIS, ROBERT, TROJANOWSKA, MARIA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035782/
https://www.ncbi.nlm.nih.gov/pubmed/23041765
http://dx.doi.org/10.3892/ijmm.2012.1150