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Difference in cytokine production and cell cycle progression induced by Epstein-Barr virus Lmp1 deletion variants in Kmh2, a Hodgkin lymphoma cell line

BACKGROUND: Epstein-Barr virus (EBV) is associated with 20-40% of Hodgkin’s Lymphoma (HL) cases. EBV-encoded latent membrane protein 1 (LMP1) is a well-known oncogenic protein and two C-terminal deletion variants, del30-LMP1 and del69-LMP1, have been described in animal models to be more tumorigenic...

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Detalles Bibliográficos
Autores principales: Sueur, Charlotte, Lupo, Julien, Mas, Philippe, Morand, Patrice, Boyer, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035821/
https://www.ncbi.nlm.nih.gov/pubmed/24886620
http://dx.doi.org/10.1186/1743-422X-11-94