Investigation of continuous effect modifiers in a meta-analysis on higher versus lower PEEP in patients requiring mechanical ventilation - protocol of the ICEM study

BACKGROUND: Categorizing an inherently continuous predictor in prognostic analyses raises several critical methodological issues: dependence of the statistical significance on the number and position of the chosen cut-point(s), loss of statistical power, and faulty interpretation of the results if a...

Descripción completa

Detalles Bibliográficos
Autores principales: Kasenda, Benjamin, Sauerbrei, Willi, Royston, Patrick, Briel, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035853/
https://www.ncbi.nlm.nih.gov/pubmed/24887172
http://dx.doi.org/10.1186/2046-4053-3-46

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035853/
https://www.ncbi.nlm.nih.gov/pubmed/24887172
http://dx.doi.org/10.1186/2046-4053-3-46

Ejemplares similares