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Deciphering the mechanism behind Fibroblast Growth Factor (FGF) induced biphasic signal-response profiles

BACKGROUND: The Fibroblast Growth Factor (FGF) pathway is driving various aspects of cellular responses in both normal and malignant cells. One interesting characteristic of this pathway is the biphasic nature of the cellular response to some FGF ligands like FGF2. Specifically, it has been shown th...

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Detalles Bibliográficos
Autores principales: Kanodia, Jitendra, Chai, Diana, Vollmer, Jannik, Kim, Jaeyeon, Raue, Andreas, Finn, Greg, Schoeberl, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036111/
https://www.ncbi.nlm.nih.gov/pubmed/24885272
http://dx.doi.org/10.1186/1478-811X-12-34