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Glucose Transporter 8 (GLUT8) Mediates Fructose-induced de Novo Lipogenesis and Macrosteatosis

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in the world, and it is thought to be the hepatic manifestation of the metabolic syndrome. Excess dietary fructose causes both metabolic syndrome and NAFLD in rodents and humans, but the pathogenic mechanisms of fructose-indu...

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Detalles Bibliográficos
Autores principales: DeBosch, Brian J., Chen, Zhouji, Saben, Jessica L., Finck, Brian N., Moley, Kelle H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036240/
https://www.ncbi.nlm.nih.gov/pubmed/24519932
http://dx.doi.org/10.1074/jbc.M113.527002