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Distinctive behavioral and cellular responses to fluoxetine in the mouse model for Fragile X syndrome

Fluoxetine is used as a therapeutic agent for autism spectrum disorder (ASD), including Fragile X syndrome (FXS). The treatment often associates with disruptive behaviors such as agitation and disinhibited behaviors in FXS. To identify mechanisms that increase the risk to poor treatment outcome, we...

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Detalles Bibliográficos
Autores principales: Uutela, Marko, Lindholm, Jesse, Rantamäki, Tomi, Umemori, Juzoh, Hunter, Kerri, Võikar, Vootele, Castrén, Maija L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036306/
https://www.ncbi.nlm.nih.gov/pubmed/24904293
http://dx.doi.org/10.3389/fncel.2014.00150