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Membrane-bound IL-12 and IL-23 serve as potent mucosal adjuvants when co-presented on whole inactivated influenza vaccines

BACKGROUND: Potent and safe adjuvants are needed to improve the efficacy of parenteral and mucosal vaccines. Cytokines, chemokines and growth factors have all proven to be effective immunomodulatory adjuvants when administered with a variety of antigens. We have previously evaluated the efficacy of...

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Detalles Bibliográficos
Autores principales: Khan, Tila, Heffron, Connie L, High, Kevin P, Roberts, Paul C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036309/
https://www.ncbi.nlm.nih.gov/pubmed/24884849
http://dx.doi.org/10.1186/1743-422X-11-78