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In vitro clinical trials: the future of cell-based profiling
The drug discovery process classically revolves around a set of biochemical and cellular assays to drive potency optimization and structural-activity relationship models. Layered on top of these concepts is the inclusion of molecular features that affect final drug use, things like: bioavailability,...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036381/ https://www.ncbi.nlm.nih.gov/pubmed/24904423 http://dx.doi.org/10.3389/fphar.2014.00121 |