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Absence of strong strain effects in behavioral analyses of Shank3-deficient mice

Haploinsufficiency of SHANK3, caused by chromosomal abnormalities or mutations that disrupt one copy of the gene, leads to a neurodevelopmental syndrome called Phelan-McDermid syndrome, symptoms of which can include absent or delayed speech, intellectual disability, neurological changes and autism s...

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Detalles Bibliográficos
Autores principales: Drapeau, Elodie, Dorr, Nate P., Elder, Gregory A., Buxbaum, Joseph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036474/
https://www.ncbi.nlm.nih.gov/pubmed/24652766
http://dx.doi.org/10.1242/dmm.013821