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Absence of strong strain effects in behavioral analyses of Shank3-deficient mice
Haploinsufficiency of SHANK3, caused by chromosomal abnormalities or mutations that disrupt one copy of the gene, leads to a neurodevelopmental syndrome called Phelan-McDermid syndrome, symptoms of which can include absent or delayed speech, intellectual disability, neurological changes and autism s...
Autores principales: | Drapeau, Elodie, Dorr, Nate P., Elder, Gregory A., Buxbaum, Joseph D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036474/ https://www.ncbi.nlm.nih.gov/pubmed/24652766 http://dx.doi.org/10.1242/dmm.013821 |
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