Phospholipase D2 Enhances Epidermal Growth Factor-Induced Akt Activation in EL4 Lymphoma Cells

Phospholipase D2 (PLD2) generates phosphatidic acid through hydrolysis of phosphatidylcholine. PLD2 has been shown to play a role in enhancing tumorigenesis. The epidermal growth factor receptor (EGFR) can both activate and interact with PLD2. Murine lymphoma EL4 cells lacking endogenous PLD2 presen...

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Detalles Bibliográficos
Autores principales: Chahal, Manpreet S., Brauner, Daniel J., Meier, Kathryn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036664/
https://www.ncbi.nlm.nih.gov/pubmed/27713341
http://dx.doi.org/10.3390/ph3072045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036664/
https://www.ncbi.nlm.nih.gov/pubmed/27713341
http://dx.doi.org/10.3390/ph3072045

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