In Silico Screening of Nonsteroidal Anti-Inflammatory Drugs and Their Combined Action on Prostaglandin H Synthase-1

The detailed kinetic model of Prostaglandin H Synthase-1 (PGHS-1) was applied to in silico screening of dose-dependencies for the different types of nonsteroidal anti-inflammatory drugs (NSAIDs), such as: reversible/irreversible, nonselective/selective to PGHS-1/PGHS-2 and time dependent/independent...

Descripción completa

Detalles Bibliográficos
Autores principales: Goltsov, Alexey, Lebedeva, Galina, Humphery-Smith, Ian, Goltsov, Gregory, Demin, Oleg, Goryanin, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036666/
https://www.ncbi.nlm.nih.gov/pubmed/27713342
http://dx.doi.org/10.3390/ph3072059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036666/
https://www.ncbi.nlm.nih.gov/pubmed/27713342
http://dx.doi.org/10.3390/ph3072059

Ejemplares similares