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The Role of Protein Modifications of T-Bet in Cytokine Production and Differentiation of T Helper Cells
T-Bet (T-box protein expressed in T cells, also called as TBX21) was originally cloned as a key transcription factor involved in the commitment of T helper (Th) cells to the Th1 lineage. T-Bet directly activates IFN-γ gene transcription and enhances development of Th1 cells. T-Bet simultaneously mod...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036734/ https://www.ncbi.nlm.nih.gov/pubmed/24901011 http://dx.doi.org/10.1155/2014/589672 |