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Optimizing the programmatic deployment of the anti-malarials artemether-lumefantrine and dihydroartemisinin-piperaquine using pharmacological modelling

BACKGROUND: Successful programmatic use of anti-malarials faces challenges that are not covered by standard drug development processes. The development of appropriate pragmatic dosing regimens for low-resource settings or community-based use is not formally regulated, even though these may alter fac...

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Detalles Bibliográficos
Autores principales: Hodel, Eva Maria, Kay, Katherine, Hayes, Daniel J, Terlouw, Dianne J, Hastings, Ian M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036747/
https://www.ncbi.nlm.nih.gov/pubmed/24708571
http://dx.doi.org/10.1186/1475-2875-13-138