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Dynamics of Posttranslational Modifications of p53

The latest experimental evidence indicates that acetylation of p53 at K164 (lysine 164) and K120 may induce directly cell apoptosis under severe DNA damage. However, previous cell apoptosis models only studied the effects of active and/or inactive p53, that is, phosphorylation/dephosphorylation of p...

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Detalles Bibliográficos
Autores principales: Fan, Qing-Duan, Wu, Guang, Liu, Zeng-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037116/
https://www.ncbi.nlm.nih.gov/pubmed/24899917
http://dx.doi.org/10.1155/2014/245610