Osteopontin Deletion Prevents the Development of Obesity and Hepatic Steatosis via Impaired Adipose Tissue Matrix Remodeling and Reduced Inflammation and Fibrosis in Adipose Tissue and Liver in Mice

Osteopontin (OPN) is a multifunctional extracellular matrix (ECM) protein involved in multiple physiological processes. OPN expression is dramatically increased in visceral adipose tissue in obesity and the lack of OPN protects against the development of insulin resistance and inflammation in mice....

Descripción completa

Detalles Bibliográficos
Autores principales: Lancha, Andoni, Rodríguez, Amaia, Catalán, Victoria, Becerril, Sara, Sáinz, Neira, Ramírez, Beatriz, Burrell, María A., Salvador, Javier, Frühbeck, Gema, Gómez-Ambrosi, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037189/
https://www.ncbi.nlm.nih.gov/pubmed/24871103
http://dx.doi.org/10.1371/journal.pone.0098398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037189/
https://www.ncbi.nlm.nih.gov/pubmed/24871103
http://dx.doi.org/10.1371/journal.pone.0098398

Ejemplares similares