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Achieving Peptide Binding Specificity and Promiscuity by Loops: Case of the Forkhead-Associated Domain
The regulation of a series of cellular events requires specific protein–protein interactions, which are usually mediated by modular domains to precisely select a particular sequence from diverse partners. However, most signaling domains can bind to more than one peptide sequence. How do proteins cre...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037201/ https://www.ncbi.nlm.nih.gov/pubmed/24870410 http://dx.doi.org/10.1371/journal.pone.0098291 |