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Impairment of Nitric Oxide Synthase but Not Heme Oxygenase Accounts for Baroreflex Dysfunction Caused by Chronic Nicotine in Female Rats

We recently reported that chronic nicotine impairs reflex chronotropic activity in female rats. Here, we sought evidence to implicate nitric oxide synthase (NOS) and/or heme oxygenase (HO) in the nicotine-baroreflex interaction. Baroreflex curves relating changes in heart rate to increases (phenylep...

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Detalles Bibliográficos
Autores principales: Fouda, Mohamed A., El-Gowelli, Hanan M., El-Gowilly, Sahar M., Rashed, Laila, El-Mas, Mahmoud M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037226/
https://www.ncbi.nlm.nih.gov/pubmed/24870610
http://dx.doi.org/10.1371/journal.pone.0098681