Strikingly poor CD8(+) T cell immunogenicity of vaccinia virus strain MVA in BALB/c mice

Vaccinia virus (VACV) strain MVA is a highly attenuated vector for vaccines that is being explored in clinical trials. We compared the CD8(+) T cell immunogenicity of MVA with that of a virulent laboratory strain of VACV (strain WR) in BALB/c mice by examining epitope-specific responses as well as e...

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Detalles Bibliográficos
Autores principales: Russell, Tiffany A., Tscharke, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037371/
https://www.ncbi.nlm.nih.gov/pubmed/24566805
http://dx.doi.org/10.1038/icb.2014.10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037371/
https://www.ncbi.nlm.nih.gov/pubmed/24566805
http://dx.doi.org/10.1038/icb.2014.10

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