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ATF4- and CHOP-Dependent Induction of FGF21 through Endoplasmic Reticulum Stress

Fibroblast growth factor 21 (FGF21) is an important endogenous regulator involved in the regulation of glucose and lipid metabolism. FGF21 expression is strongly induced in animal and human subjects with metabolic diseases, but little is known about the molecular mechanism. Endoplasmic reticulum (ER...

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Detalles Bibliográficos
Autores principales: Wan, Xiao-shan, Lu, Xiang-hong, Xiao, Ye-cheng, Lin, Yuan, Zhu, Hong, Ding, Ting, Yang, Ying, Huang, Yan, Zhang, Yi, Liu, Yan-Long, Xu, Zhu-mei, Xiao, Jian, Li, Xiao-kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037570/
https://www.ncbi.nlm.nih.gov/pubmed/24900988
http://dx.doi.org/10.1155/2014/807874