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Active angiogenesis in metastatic renal cell carcinoma predicts clinical benefit to sunitinib-based therapy
BACKGROUND: Sunitinib represents a widely used therapy for metastatic renal cell carcinoma patients. Even so, there is a group of patients who show toxicity without clinical benefit. In this work, we have analysed pivotal molecular targets involved in angiogenesis (vascular endothelial growth factor...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037833/ https://www.ncbi.nlm.nih.gov/pubmed/24786599 http://dx.doi.org/10.1038/bjc.2014.225 |