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Serum levels of hepatocyte growth factor and epiregulin are associated with the prognosis on anti-EGFR antibody treatment in KRAS wild-type metastatic colorectal cancer

BACKGROUND: Ligands of transmembrane receptor tyrosine kinases have important roles in cell proliferation, survival, migration and differentiation in solid tumours. We conducted this study to evaluate the relationship between concentration of serum ligands and prognosis of patients with metastatic c...

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Detalles Bibliográficos
Autores principales: Takahashi, N, Yamada, Y, Furuta, K, Honma, Y, Iwasa, S, Takashima, A, Kato, K, Hamaguchi, T, Shimada, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037834/
https://www.ncbi.nlm.nih.gov/pubmed/24800946
http://dx.doi.org/10.1038/bjc.2014.230