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Serum levels of hepatocyte growth factor and epiregulin are associated with the prognosis on anti-EGFR antibody treatment in KRAS wild-type metastatic colorectal cancer
BACKGROUND: Ligands of transmembrane receptor tyrosine kinases have important roles in cell proliferation, survival, migration and differentiation in solid tumours. We conducted this study to evaluate the relationship between concentration of serum ligands and prognosis of patients with metastatic c...
Autores principales: | Takahashi, N, Yamada, Y, Furuta, K, Honma, Y, Iwasa, S, Takashima, A, Kato, K, Hamaguchi, T, Shimada, Y |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037834/ https://www.ncbi.nlm.nih.gov/pubmed/24800946 http://dx.doi.org/10.1038/bjc.2014.230 |
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