Rapid inflammasome activation in microglia contributes to brain disease in HIV/AIDS

BACKGROUND: Human immunodeficiency virus type 1(HIV-1) infects and activates innate immune cells in the brain resulting in inflammation and neuronal death with accompanying neurological deficits. Induction of inflammasomes causes cleavage and release of IL-1β and IL-18, representing pathogenic proce...

Descripción completa

Detalles Bibliográficos
Autores principales: Walsh, John G, Reinke, Stacey N, Mamik, Manmeet K, McKenzie, Brienne A, Maingat, Ferdinand, Branton, William G, Broadhurst, David I, Power, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038111/
https://www.ncbi.nlm.nih.gov/pubmed/24886384
http://dx.doi.org/10.1186/1742-4690-11-35

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038111/
https://www.ncbi.nlm.nih.gov/pubmed/24886384
http://dx.doi.org/10.1186/1742-4690-11-35

Ejemplares similares