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Rapid inflammasome activation in microglia contributes to brain disease in HIV/AIDS

BACKGROUND: Human immunodeficiency virus type 1(HIV-1) infects and activates innate immune cells in the brain resulting in inflammation and neuronal death with accompanying neurological deficits. Induction of inflammasomes causes cleavage and release of IL-1β and IL-18, representing pathogenic proce...

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Detalles Bibliográficos
Autores principales:	Walsh, John G, Reinke, Stacey N, Mamik, Manmeet K, McKenzie, Brienne A, Maingat, Ferdinand, Branton, William G, Broadhurst, David I, Power, Christopher
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038111/ https://www.ncbi.nlm.nih.gov/pubmed/24886384 http://dx.doi.org/10.1186/1742-4690-11-35

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