The Carbamoylmannose Moiety of Bleomycin Mediates Selective Tumor Cell Targeting

[Image: see text] Recently, we reported that both bleomycin (BLM) and its disaccharide, conjugated to the cyanine dye Cy5**, bound selectively to cancer cells. Thus, the disaccharide moiety alone recapitulates the tumor cell targeting properties of BLM. Here, we demonstrate that the conjugate of the...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Chandrabali, Yu, Zhiqiang, Rishel, Michael J., Hecht, Sidney M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038340/
https://www.ncbi.nlm.nih.gov/pubmed/24811347
http://dx.doi.org/10.1021/bi500482q

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038340/
https://www.ncbi.nlm.nih.gov/pubmed/24811347
http://dx.doi.org/10.1021/bi500482q

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