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The Carbamoylmannose Moiety of Bleomycin Mediates Selective Tumor Cell Targeting
[Image: see text] Recently, we reported that both bleomycin (BLM) and its disaccharide, conjugated to the cyanine dye Cy5**, bound selectively to cancer cells. Thus, the disaccharide moiety alone recapitulates the tumor cell targeting properties of BLM. Here, we demonstrate that the conjugate of the...
Autores principales: | Bhattacharya, Chandrabali, Yu, Zhiqiang, Rishel, Michael J., Hecht, Sidney M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038340/ https://www.ncbi.nlm.nih.gov/pubmed/24811347 http://dx.doi.org/10.1021/bi500482q |
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