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The Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal-Derived AGEs
[Image: see text] Diabetes-induced hyperglycemia increases the extracellular concentration of methylglyoxal. Methylglyoxal-derived hydroimidazolones (MG-H) form advanced glycation end products (AGEs) that accumulate in the serum of diabetic patients. The binding of hydroimidozolones to the receptor...
Autores principales: | Xue, Jing, Ray, Rashmi, Singer, David, Böhme, David, Burz, David S., Rai, Vivek, Hoffmann, Ralf, Shekhtman, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038343/ https://www.ncbi.nlm.nih.gov/pubmed/24824951 http://dx.doi.org/10.1021/bi500046t |
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