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Identification and Validation of Novel PERK Inhibitors

[Image: see text] PERK, as one of the principle unfolded protein response signal transducers, is believed to be associated with many human diseases, such as cancer and type-II diabetes. There has been increasing effort to discover potent PERK inhibitors due to its potential therapeutic interest. In...

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Detalles Bibliográficos
Autores principales: Wang, Qiantao, Park, Jihyun, Devkota, Ashwini K., Cho, Eun Jeong, Dalby, Kevin N., Ren, Pengyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038368/
https://www.ncbi.nlm.nih.gov/pubmed/24745945
http://dx.doi.org/10.1021/ci500114r