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Inhibition of hepatitis C virus by an M1GS ribozyme derived from the catalytic RNA subunit of Escherichia coli RNase P

BACKGROUND: Hepatitis C virus (HCV) is a human pathogen causing chronic liver disease in about 200 million people worldwide. However, HCV resistance to interferon treatment is one of the important clinical implications, suggesting the necessity to seek new therapies. It has already been shown that s...

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Detalles Bibliográficos
Autores principales: Mao, Xinliang, Li, Xifang, Mao, Xinjun, Huang, Zhiwen, Zhang, Chengcheng, Zhang, Wenjun, Wu, Jianguo, Li, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038377/
https://www.ncbi.nlm.nih.gov/pubmed/24885776
http://dx.doi.org/10.1186/1743-422X-11-86